Bute can usually be used for 5 – 7 days with no adverse effects. But what if you need to treat with bute long term? Thankfully you don’t need to cut off pain relief at 7 days because there IS a solution: gastrointestinal protectants like sucralfate are frequently included as part of BUTE treatment for long-term use.
How does bute work?
Bute (otherwise known as Phenylbutazone) functions by blocking the enzymes that contribute to pain and inflammation. However, in this process, the beneficial enzyme that maintains a healthy gastrointestinal lining is also blocked.
Over a period of 5-7 days this makes the mucosal lining of the stomach more vulnerable to stomach acid potentially leading to ulcerations anywhere along the digestive tract.
How does sucralfate help?
Sucralfate forms a paste that provides a direct protective barrier for up to 6 hours. This protective barrier replaces the enzyme protectant that is blocked by bute.
However, it’s important to note that the protective barrier formed by sucralfate can also inhibit the absorption of other medications and vitamins.
For this reason, sucralfate must be fed 60 mins before or after other medications. See more about treating with sucralfate here.
If you have a horse requiring long-term pain relief you can get both bute and sucralfate online without a prescription from Abler.